·         Granny – She offers professional love and care for the babies to keep them happy. The babies are fascinated and touched by her wisdom and her ability to overcome problems when they arise.

·         Floyd Minton – Granny's nephew. Sometimes he is overwhelmed by the responsibility he takes on the babies but he is determined never to let Granny down. He often keeps an eye on one of the individual babies in each episode during Season 2.

·         Baby Sylvester – At times he is shy and hesitant and he makes an easy target for Daffy to hoax and trade with. He is rarely seen using his claws. He likes to get attention from Granny more than the others.

·         Baby Tweety – The youngest and the smallest of the gang. Depicted as the brainstormer, because he comes up with ideas when the others are fresh out of them. He is very sensitive about his small frame (which he must overcome in most episodes centered around him) and curious about what he encounters.

·         Baby Taz – As much as Taz is well behaved, he often mistakes various objects for food and sometimes breaks things with his spin. He has a sense of fun which exceeds all the others and he is prone to being a cry baby.

·         Baby Petunia – She often sticks with Melissa. She is smarter than the other babies with insatiable curiosity.

·         Baby Melissa – She often sticks with Petunia. She is a highly ambitious and thoughtful sort with a good nature, but at times she can be a control freak and get on the others nerves.

·         Baby Daffy – Often he is self-indulgent and always wants his personal gain. When problems arise, he believes it is himself who is treated unfairly, not noticing the inconvience inflicted on the others. Half the time, he does show and mean good intent.

·         Baby Lola – She is second in the lead after Bugs but sometimes she takes charge. Her independence is greater than the others and she has more boyish tendencies than the other girls.

·         Baby Bugs – He is indicated to be the oldest of the babies, which validates him as the leader. His leadership however does tend to cause dispute, especially with Lola and Daffy.